https://petermcculloughmd.substack.com/ ... cular-mrna
BREAKING STUDY: Intramuscular mRNA Injections Distribute to Vital Organs, Resulting in Systemic Spike Protein Production
Spike protein expression observed in critical organs, including the liver, spleen, lungs, heart, head, and kidneys.
Even at low doses (0.0005 mg/kg), systemic distribution of LNPs and translated mRNA was measurable. These data demonstrate that COVID-19 mRNA injection LNPs systemically circulate and are taken up into vital organ systems resulting in body-wide toxic Spike protein production. This helps to explain why autopsies find widespread dissemination of ‘vaccine’ spike protein in various tissues and organs:
Autopsies Find Widespread Dissemination of Vaccine Spike Protein In Various Tissues and Organs
Lets look at some "fact checking" regarding the mRNA staying in the arm:
https://apnews.com/article/fact-checking-377989296609
In the interview, Bridle says that the spike proteins generated by the vaccines don’t stay in the shoulder muscle, but spread and are “causing so much damage in other parts of the bodies of the vaccinated.” But Dr. Adam Ratner, a pediatric infectious disease specialist at NYU Langone Health, said that vaccines are mostly concentrated at the site of injection or the local lymph nodes.
“What was said in the radio show was completely inaccurate,” Ratner said. “There is no spike protein in the vaccines first of all. The amounts that are made after the mRNA is injected are very small and it almost exclusively stays locally. It is nowhere near the amount he was talking about.”
In the radio interview, Bridle mentions a study of 13 health care workers that he said confirmed that the spike in protein was found in their blood. But experts say they found nothing of concern from that same study, which was conducted by researchers at Brigham and Women’s Hospital and appeared in the journal Clinical Infectious Diseases in May.
https://www.nebraskamed.com/COVID/where ... roteins-go
Where does the vaccine go?
Here's a peer-reviewed study that shows where intramuscular vaccines (which all three of the COVID-19 vaccines are) travel in macaques (a type of monkey). Vaccines mostly remain near the site of injection (the arm muscle) and local lymph nodes.
This makes sense: Lymph nodes produce white blood cells and antibodies to protect us from disease. A key part of the lymphatic system, lymph nodes also clean up fluids and remove waste materials. Finding pieces of spike protein in the lymph nodes is completely normal, because lymph nodes act as the trash removal service for the body. That means the vaccine did its job (made spike proteins, which caused the creation of antibodies) and will be cleared from the body.
Another peer-reviewed study tested exactly where an mRNA vaccine went in mice. Most of the mRNA vaccine stayed in the injection site muscle – where you get the shot. Look at Table 1. A lot of mRNA vaccine was found in local lymph nodes, which peaked about eight hours after the shot was given. A much smaller amount of mRNA vaccine went to farther away lymph nodes.
https://www.quora.com/Is-it-true-that-t ... loodstream
Amy Chai
MD, Internal Medicine, MS EpidemiologyAuthor has 8.2K answers and 176.5M answer views3y
mRNA degrades EXTREMELY rapidly. That is why they need to keep it in the deep freeze and discard anything left over that has thawed out. It lasts a few hours at room temperature. At body temperature, we are talking gone in a very very brief time.
It is not injected IV (intravenous). It is injected IM (intramuscular). It is unlikely to be able to survive long enough to get into the general circulation, but if it did, who cares? It wouldn’t harm your blood cells. Your blood cells don’t even have nuclei in them. They extrude their nuclei during bone marrow development to become biconcave carriers of hemoglobin. And if white blood cells contact the mRNA, well cool. Good job.
So I am baffled by this question. The only people who might be concerned about mRNA in the blood are people who don’t know anything about biology. And the only people who worry about IV injection from an IM injection are people who are not nurses or doctors.
So the answer is, NO. And also if the answer would have been YES, there is a big shrug because who cares?
The mRNA is degraded within a few hours of the injection and does not remain intact as your body uses it as junk to be broken down and recycled.
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Aug 17
The idea that mRNA vaccines, such as the COVID-19 vaccines, leave the shoulder muscle and spread into the bloodstream is a misconception. Here's a more detailed explanation:
Mechanism of Action: mRNA vaccines work by introducing a small piece of messenger RNA (mRNA) into the body. This mRNA instructs cells to produce a harmless piece of the spike protein found on the surface of the virus that causes COVID-19. The immune system then recognizes this protein as foreign and mounts an immune response.
Injection Site: When the vaccine is injected into the shoulder muscle (deltoid), it primarily stays in the muscle tissue and the nearby lymph nodes. The mRNA does not circulate freely in the bloodstream; rather, it is taken up by cells at the injection site and nearby lymph nodes.
Rapid Breakdown: The mRNA from the vaccine is rapidly broken down and does not persist in the body for long. It is designed to instruct cells to produce the spike protein and then degrades within hours to days.
Safety and Monitoring: Extensive clinical trials and ongoing monitoring have shown that mRNA vaccines are safe and effective. Concerns about spreading through the bloodstream are not supported by scientific evidence.
In summary, while the mRNA from vaccines is taken up by the body, it does not spread into the bloodstream in a way that would raise concerns about safety or efficacy.
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Jeffrey Diver
Retired ref. asst. Cornell U. Lib.: 5.1M+ views 8.8K answersAuthor has 6.2K answers and 1.5M answer views1y
Eli Duran,
NO.
The biologically ignorant suggestion “that the mRNA shot is leaving the shoulder muscle and spreading into the bloodstream” is a fiction designed to scare folks away from mRNA vaccines.[1]
It reminds some of us of the idiotic rumors that used to surround the invention of the “horseless carriage” - the automobile. At that time we were told it would impair our health if we exceeded the travelling speed of 20 miles per hour — in, of course, one of those new-fangled, dangerous, poopless machines.
By all means, avoid modern conveyances of any kind![2]
https://factcheck.afp.com/us-doctor-spr ... a-vaccines
No evidence of risk to blood-brain barrier
In the video, Cole also claims that spike proteins can “break through the blood-brain barrier and cause brain damage”. AFP Fact Check previously debunked this claim in Serbian here.
Daniel Dunia, director of research at the French National Centre for Scientific Research (CNRS), said at the time that the mRNA vaccine was injected locally into the muscle, and the effect of spike proteins would be limited to the initial cells that the vaccine targets to elicit an immune response. mRNA is unstable and will degrade quickly.
“Even when a person suffers from a serious Covid infection, there is no direct evidence that damage to the BBB (blood-brain barrier) is directly related to the virus,” he added.
Contacted again on August 13, 2021, Dunia confirmed to AFP Fact Check that there is currently no scientific evidence to claim that mRNA vaccines cause neurodegenerative diseases.
“Moreover, there are no reported neurological side effects associated with the mRNA vaccine, if you exclude the classic temperature that you have with many vaccines,” he said.
https://pssjournal.biomedcentral.com/ar ... 21-00291-9
COVID-19 mRNA vaccination mechanism. The mRNA vaccine is injected by intramuscular route, typically into the deltoid muscle. The lipid coat vehicle around the mRNA allows for the vaccine to enter the cytosol of the cell. The ribosomes translate the mRNA into spike proteins. The injected mRNA subsequently degrades. The spike proteins are released from the cell and initiate an adaptive immune response. Through various activation pathways, immune cells mount a cell-mediated and antibody-mediated immunity against the spike protein of the SARS-CoV-2 virus
https://www.cdc.gov/covid/vaccines/how- ... 20protein.
How mRNA COVID-19 vaccines work
First, mRNA COVID-19 vaccines are given in the upper arm muscle or upper thigh, depending on the age of who is getting vaccinated.
After vaccination, the mRNA will enter the muscle cells. Once inside, they use the cells’ machinery to produce a harmless piece of what is called the spike protein. The spike protein is found on the surface of the virus that causes COVID-19. After the protein piece is made, our cells break down the mRNA and remove it, leaving the body as waste.
https://www.cell.com/molecular-therapy- ... 23)00301-3
The results of this study provide essential information on the path that our mRNA-LNP vaccine takes following i.m. administration and the time course of detection in select tissues critical to generating an immune response. After i.m. delivery of mRNA-LNPs, we demonstrated that mRNA distribution and protein expression are seen primarily in infiltrating immune cells in both NHPs and rodents at the injection site, followed by expression in the dLNs. Within the dLN, macrophages exhibit the greatest level of protein expression. These data will help us optimize our mRNA-LNP system for future vaccines and provide important guidance on developing mRNA vaccines.
https://individual.carefirst.com/indivi ... -work.page
How does the mRNA COVID-19 vaccine work?
Both the Pfizer BioNTech (Pfizer) vaccine and Moderna Vaccine/Spikevax COVID-19 Vaccine (Spikevax) contain strands of genetic material called mRNA. mRNA stands for Messenger RNA. It tells your DNA how to make specific proteins. The mRNA contains instructions that your body can read to create a special type of protein. This protein triggers your immune system, which then creates antibodies specific to COVID-19. This is how the vaccines protect your body from the virus.
Once the mRNA does its job, your body destroys it and it’s flushed from your system.
“Thou shalt not bow down thyself to them, nor serve them: for I the LORD thy God am a jealous God, visiting the iniquity of the fathers upon the children unto the third and fourth generation of them that hate me; - Exodus 20:5